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Frederika Kaestle

Frederika Kaestle

Associate Professor of Anthropology
Director, Ancient DNA Laboratory of Molecular Anthropology
Fellow, Indiana Molecular Biology Institute
Affiliate Faculty, William R. Adams Zooarchaeology Lab

(812) 855-3164 | Email | Office Hours
  • Ph.D. in Anthropology, University of California, Davis (1998)
  • M.A. in Anthropology, University of California, Davis (1994)
  • B.A. in Anthropology, Yale University (1992), Summa cum Laude, Exceptional Distinction in Anthropology

Geographical Areas of Specialization: Native America, Pacific, Asia

Topical Interests: Molecular anthropology, molecular evolution, population genetics, ancient DNA

Profile:

During my academic career I have specialized in molecular genetic techniques that can be utilized to address anthropological questions. Over the past decade I have concentrated on the new techniques and protocols that make ancient DNA available for study, and have used these data to test hypotheses based on archaeological, linguistic, and ethnographic studies. Anthropologists have struggled with the relationship between biology and culture - how do we identify biological relationships in prehistory using cultural and skeletal remains? Conventional anthropological analysis of skeletal material has often failed to clarify complex issues of social organization and structure, including residence and mating patterns, and kinship systems. Multiple burials are also a well-known feature of prehistoric mortuary behavior, but traditional archaeological methods often do not provide much insight into the meanings and implications of this pattern because the relationships of the individuals associated in multiple burials are not known. On a larger scale, similarities in material culture have been considered signals of biological continuity or contact in prehistory, while abrupt changes in material culture or morphology have been taken as signs of biological replacement. Further conflation of material culture and morphological similarities with biological populations often occurs in assessing prehistoric patterns of population movement over long distances, on occasion accompanied by supporting data from modern linguistic relationships. Thus material culture, language, and morphology become proxies for ethnicity, which is conflated with the biological concept of a population. Although in many modern cases these classes of data map onto each other rather well, their conflation in prehistory is problematic given the numerous examples of their discontinuity in contemporary and historic groups. Ancient DNA provides us with another source of data relevant to these issues, and in many cases allows the first direct tests of some of these hypotheses.

In my research I have looked at several instances of hypothesized prehistoric population movement and replacement, such as the Numic Expansion in the Great Basin, the initial peopling of the New World, and the settlement of the Pacific, in an effort to determine which archaeological signals are the most reliable indicators of prehistoric migrations and relationships and to refine current hypotheses regarding these specific instances of possible population movement. In addition, my previous projects and current research interests have included much more fine-grained analyses of kinship and residence and burial patterns. In general, kinship and sex are the primary structural elements upon which ancient social organization was based. These parameters determined inter- and intra-community relationships, status and position within the socio-political hierarchy, and inheritance of social prerogatives. Traditionally, kinship and sex have been assessed through archaeological context and conventional physical anthropological analysis. These analyses, however, are limited by factors such as the degree of preservation of the remains, ambiguities in physical markers and researcher bias. The study of aDNA (ancient DNA) provides a means to mitigate some of these limitations by enabling genetic discrimination of kinship and precise determination of sex for burials in which hard tissue has been preserved. Ancient DNA data may determine whether relationships were based on blood (consanguineal), marriage (affinal), or other systems, and can contribute greatly to our understanding of differential patterns of mortality, disease, diet, burial, and material culture based on sex or kinship.
My current research projects are described at http://php.indiana.edu/~molanth/ .


Selected Publications


2001 Kaestle, FA and DG Smith. Ancient Native American DNA from Western Nevada: Implications for the Numic Expansion Hypothesis. American Journal of Physical Anthropology. 115:1-12.
2000 Kaestle, FA Report on DNA Analyses of the Remains of "Kennewick Man" from Columbia Park, Washington. Chapter 2 in Report on the DNA Testing Results of the Kennewick Human Remains from Columbia Park, Kennewick, Washington. National Parks Service website http://www.cr.nps.gov/aad/kennewick/index.htm.
1999 Merriwether, DA, FA Kaestle, B Zemel, G Koki, C Mogne, M Alpers and J Friedlaender. Mitochondrial DNA Variation in the Southwest Pacific. In SS Papiha, R Deka, R Chakraborty (eds.) Genomic Diversity: Applications in Human Population Genetics. New York: Kluwer Academic/Plenum Publishers. pp. 153-182.
1999 Kaestle, FA, JG Lorenz, and DG Smith. Molecular Genetics and the Numic Expansion: A Molecular Investigation of the Prehistoric Inhabitants of Stillwater Marsh. In BE Hemphill and CS Larsen (eds.) Understanding Prehistoric Lifeways in the Great Basin Wetlands: Bioarchaeological Reconstruction and Interpretation. Salt Lake City: University of Utah Press. pp. 167-183.
1999 Merriwether, DA and FA Kaestle. Mitochondrial Recombination? (Continued). Science 285:837.
1999 Smith, DG, RS Malhi, J Eshleman, JG Lorenz, and FA Kaestle. Distribution of mtDNA Haplogroup X among Native North Americans. American Journal of Physical Anthropology 110(3):271-284.
1997 Molecular Analysis of Ancient Native American DNA from Western Nevada. Nevada Historical Society Quarterly 40(1):85-96.
1996 Mitochondrial DNA Evidence for the Identity of the Descendants of the Prehistoric Stillwater Marsh Population. In CS Larsen and RL Kelly (eds.) Bioarchaeology of the Stillwater Marsh: Prehistoric Human Adaptation in the Western Great Basin. Anthropological Papers of the American Museum of Natural History 77:73-80.
1994 Book Review: Ancient DNA: Recovery and Analysis of Genetic Material from Paleontological, Archaeological, Museum, Medical, and Forensic Specimens. B. Herrmann and S. Hummel (eds.) New York: Springer Verlag. American Journal of Physical Anthropology 95(1):107-109.
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